For prescribers, neurologists, psychiatrists, pharmacists and therapists whose patients ask about supplements. A consumer asks whether a supplement works. You ask what is in it, how much, what it interacts with, and whether the label can be trusted.
One Proco product discloses every active at its individual amount: Sleep Formula. That is the only one that qualifies, and we won't claim otherwise about the range.
Two more have nothing to hide because they are effectively single-ingredient: Omega-3 and Magnesium Glycinate.
Two do not: Cognitive Support and Sleep Support. Both carry proprietary blends. In September 2026 our manufacturer confirmed that the individual amounts inside those blends cannot be published. There is no timeline for that changing, and we have stopped saying there is one. If you need to know the dose of a specific active in either of those two products, we cannot tell you, and neither can anyone else.
We think you should know that before you consider suggesting either.
Each status below is checkable against the Supplement Facts panel on the pack.
Seven actives, every amount printed. No blend.
Single-ingredient fish oil. EPA and DHA both stated.
One active, one amount. Nothing to hide.
Two vitamins disclosed; eight actives inside a 255 mg blend.
Four disclosed; fourteen named actives inside a 905 mg blend.
| Active | Amount |
|---|---|
| Valerian extract (root) | 150 mg |
| Chamomile extract (flower) | 100 mg |
| GABA | 100 mg |
| L-Tryptophan | 100 mg |
| Lemon balm extract (Melissa officinalis) | 100 mg |
| Passion flower extract | 100 mg |
| Melatonin | 2 mg |
Gelatin capsule with brown rice flour — not vegan. 60 capsules; the amounts above are per two-capsule daily serving. No proprietary blend — every number is on the panel.
This product shows the difference plainly: chamomile is 100 mg against the 800 mg/day used in the trial we cite, and lemon balm is 100 mg against the 1,600 mg at which its clearest acute effects appeared. The point of publishing every number is that you can see that for yourself.
| Active | Per softgel | Two softgels |
|---|---|---|
| Fish oil | 1,000 mg | 2,000 mg |
| EPA | 180 mg | 360 mg |
| DHA | 120 mg | 240 mg |
Also contains vitamin E. Softgel is gelatin, glycerin and water — not vegan. 100 softgels, one softgel twice daily.
The label declares Contains: Fish (sardines, anchovies). Two species, not one — worth knowing for a patient with a species-specific fish allergy.
| Active | Amount |
|---|---|
| Elemental magnesium (65% DV) | 275 mg |
| from magnesium glycinate | 2,500 mg |
Per three-capsule serving. 90 capsules, so 30 servings. One active.
Hypromellose capsule; other excipients are magnesium stearate, silicon dioxide and rice flour. We do not claim vegan status: the magnesium stearate source is not stated on the label, so we can't stand behind it.
| Component | Amount |
|---|---|
| Niacin (as niacinamide) | 8 mg NE |
| Vitamin B6 (as pyridoxine HCl) | 5 mg (290% DV) |
| Proprietary blend — 8 actives | 255 mg total |
The blend contains eight actives: GABA, L-tyrosine, caffeine, Bacopa monnieri, phosphatidylserine, alpha-GPC, L-theanine and huperzine A. Ten actives in total, two disclosed individually, eight not.
Gelatin capsule with brown rice flour — not vegan. 30 capsules, one capsule daily. Two sourcing details that come up: the phosphatidylserine is 20% from sunflower, not soy, which matters for a soy-allergic patient; the huperzine A is a 1% Huperzia serrata extract.
The Bacopa meta-analysis used standardised extract at 300–450 mg/day. The alpha-GPC trial used 315 mg or 630 mg. The L-theanine and caffeine trial used 100 mg + 50 mg. Every one of those figures is at or above the entire 255 mg blend, which holds eight ingredients. So whatever the individual amounts are, several of these actives are necessarily present well below the doses that were studied. We can't tell you the numbers, but we can tell you that much from the label, and a prescriber can reason from it.
Three further things a prescriber should note. First, the blend contains caffeine at an undisclosed amount — we cannot tell you how much, and we won't characterise it as small or large, because we don't get to describe a number we won't print. Second, it contains huperzine A, a cholinesterase inhibitor, also at an undisclosed amount. Third, 5 mg of B6 is 290% of the US Daily Value.
| Component | Amount |
|---|---|
| Vitamin B6 | 1.8 mg |
| Calcium | 17 mg |
| Magnesium (3% DV) | 13 mg |
| Melatonin | 10 mg |
| Proprietary blend — 14 ingredients | 905 mg total |
Hypromellose capsule. Contains magnesium stearate of unstated source, so as with Magnesium Glycinate we do not claim vegan status.
All 14 blend ingredients are named on the label, even though none carries an individual amount: L-tryptophan, lycium, chamomile, lemon balm, passion flower, L-taurine, hops, St John's Wort, GABA, Chinese skullcap, L-theanine, ashwagandha, inositol and 5-HTP.
The two that matter most clinically are St John's Wort and 5-HTP, and they are the reason this product needs a prescriber's attention rather than a patient's judgement.
Three further things. The magnesium is 13 mg, three percent of the Daily Value and a token amount; if a patient wants magnesium this is the wrong product and our Magnesium Glycinate delivers 275 mg elemental. The melatonin is 10 mg, five times Sleep Formula's 2 mg and above the roughly 4 mg where pooled trial data puts the peak effect on sleep onset. And a naming trap worth knowing: the blend is printed on the label as the "Sleep Formula Proprietary Blend", which is an internal label name and has nothing to do with our separate Sleep Formula product. The two are different formulas with different ingredients.
EFSA reduced the tolerable upper intake for vitamin B6 to 12 mg/day in 2023, down from 25 mg. The US Food and Nutrition Board upper limit remains 100 mg.
A patient taking both Cognitive Support (5 mg) and Sleep Support (1.8 mg) reaches 6.8 mg/day — about 57% of the EFSA limit from these products alone, before diet or any other supplement. Inside the limit, but not roomy, and worth knowing if a patient is stacking.
These are the label-level cautions we think matter most in practice. They are not a substitute for your own reference sources.
It contains St John's Wort and 5-HTP, both at undisclosed amounts inside the blend.
St John's Wort induces CYP3A4 and P-glycoprotein and reduces plasma levels of a long list of drugs. The label specifically names hormonal contraceptives, anticoagulants, antidepressants, anti-rejection medication — ciclosporin and tacrolimus, where the documented outcome has been acute rejection of a transplanted organ — HIV medication, anticonvulsants used in epilepsy: carbamazepine, phenobarbitone and phenytoin, with a stated risk of breakthrough seizures — and triptans taken for migraine, sumatriptan and naratriptan.
5-HTP carries serotonergic interaction risk with antidepressants, triptans and other serotonin-affecting agents.
A patient on an SSRI, an anticonvulsant, a triptan, a transplant regimen, warfarin or a combined oral contraceptive should not be taking Sleep Support without your input. The product page carries this warning, but a patient browsing for a sleep aid may not read it as a contraindication, and the amounts are not published so there is no way to reason about dose.
The rest, in rough order of how often they come up:
No published certificates of analysis. None. If anyone cites batch COAs for Proco, they are wrong.
No named testing laboratory, no accreditation scope, no NSF, USP or Informed Sport enrolment. We do not describe our products as third-party tested, because we cannot point you at a certificate.
No gluten-free statement on any Supplement Facts panel. Two product pages — Omega-3 and Magnesium Glycinate — display gluten-free, lactose-free, hormone-free, antibiotic-free, non-GMO and corn-free badges, and Omega-3 additionally a "no fillers" badge. Cognitive Support and Sleep Formula show only non-GMO; Sleep Support shows none. Those badges are not backed by a published certificate or a named accreditation, and we would rather tell you that than let them stand as certifications.
Two of five products are vegan — Sleep Support and, on the capsule alone, Magnesium Glycinate.
No Rx products, no diagnostics, no clinical services. These are food supplements. Nothing we sell diagnoses, treats, prevents or cures any condition, and nothing we sell is a substitute for assessment or treatment.
We don't make disease-treatment or diagnostic claims for any of these products, and we won't, regardless of what a patient has read elsewhere.
Where the evidence for an ingredient is weak, mixed or confined to populations unlike your patient, we say so in our writing rather than leaving it out — including when that argues against buying from us. We have published corrections on 82 of our own posts after auditing them, and we would rather you found that out from us than from the posts.
Two reasons for this page, and the second is self-interested. The first is that a prescriber asked a dose question we couldn't answer, and the honest response was to publish the gap rather than describe around it. The second is that we would like clinicians to feel able to point patients at us without worrying what they will find. That is only possible if the composition is on the table — including the two products where it isn't complete.
If you want something here we haven't published, ask. If the answer is that we don't know, that is what you'll get.
Everything for your brain. One company covering focus, sleep, stress and mood.
hello@procohq.com · procohq.com · Editorial standards
Composition details are taken from the current product labels and were last checked on 17 October 2026. Labels change; if you are making a clinical decision, check the panel on the pack your patient is actually holding.
This page is a composition reference, not medical advice, and it has not been reviewed by a clinician on our side. Statements about our products have not been evaluated by the Food and Drug Administration, and our products are not intended to diagnose, treat, cure or prevent any disease.
The five labels referenced above, in full: Sleep Formula · Omega-3 · Magnesium Glycinate · Cognitive Support · Sleep Support